NAADP regulates human platelet function.
Platelets play a vital role in maintaining haemostasis. Human platelet activation depends on Ca2+ release, leading to cell activation, granule secretion and aggregation. NAADP (nicotinic acid-adenine dinucleotide phosphate) is a Ca2+-releasing second messenger that acts on acidic Ca2+ stores and is...
Main Authors: | Coxon, C, Lewis, A, Sadler, A, Vasudevan, SR, Thomas, A, Dundas, K, Taylor, L, Campbell, R, Gibbins, J, Churchill, G, Tucker, K |
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Format: | Journal article |
Language: | English |
Published: |
2012
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