Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

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Type 2 diabetes affects over 300 million people, causing severe complications and premature death, yet the underlying molecular mechanisms are largely unknown. Pancreatic islet dysfunction is central in type 2 diabetes pathogenesis, and understanding islet genome regulation could therefore provide v...

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Bibliographische Detailangaben
Hauptverfasser: Pasquali, L, Gaulton, K, Rodríguez-Seguí, SA, Mularoni, L, Miguel-Escalada, I, Akerman, I, Tena, J, Morán, I, Gómez-Marín, C, Van De Bunt, M, Ponsa-Cobas, J, Castro, N, Nammo, T, Cebola, I, García-Hurtado, J, Maestro, M, Pattou, F, Piemonti, L, Berney, T, Gloyn, A, Ravassard, P, Skarmeta, J, Müller, F, Mccarthy, M, Ferrer, J
Format: Journal article
Sprache:English
Veröffentlicht: Nature Publishing Group 2014

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