Quantitative NMR analysis of Erk activity and inhibition by U0126 in a panel of patient-derived colorectal cancer cell lines.

We comparatively analyzed the basal activity of extra-cellular signal-regulated kinase (Erk1/2) in lysates of 10 human colorectal cancer cell lines by semi-quantitative Western blotting and time-resolved NMR spectroscopy. Both methods revealed heterogeneous levels of endogenous Erk1/2 activities in...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Rose, H, Stuiver, M, Thongwichian, R, Theillet, F, Feller, S, Selenko, P
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2013