Challenges in developing a controlled human tuberculosis challenge model

Challenges in developing a controlled human tuberculosis challenge model

Controlled human infection models (CHIMs) have provided pivotal scientific advancements, contributing to the licensure of new vaccines for many pathogens. Despite being one of the world’s oldest known pathogens, there are still significant gaps in our knowledge surrounding the immunobiology of Mycob...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Jackson, S, McShane, H
स्वरूप:	Book section
भाषा:	English
प्रकाशित:	Springer 2022

समान संसाधन

Controlled human infection models in COVID-19 and tuberculosis: current progress and future challenges
द्वारा: Morrison, H, और अन्य
प्रकाशित: (2023)

Insights and challenges in tuberculosis vaccine development
द्वारा: McShane, H
प्रकाशित: (2019)

Tuberculosis vaccines: Progress and challenges
द्वारा: Checkley, A, और अन्य
प्रकाशित: (2011)

Exploring the ethics of tuberculosis human challenge models
द्वारा: Rohrig, A, और अन्य
प्रकाशित: (2023)

Controlled human infection models: is it really feasible to give people tuberculosis?
द्वारा: McShane, H
प्रकाशित: (2020)

Human and Bovine Tuberculosis
द्वारा: McShane, H
प्रकाशित: (2016)

Development of a BCG challenge model for the testing of vaccine candidates against tuberculosis in cattle
द्वारा: Villarreal-Ramos, B, और अन्य
प्रकाशित: (2017)

Tuberculosis vaccines: progress and challenges.
द्वारा: Checkley, A, और अन्य
प्रकाशित: (2011)

A New Vaccine for Tuberculosis: The Challenges of Development and Deployment
द्वारा: Fletcher, H, और अन्य
प्रकाशित: (2009)

Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges
द्वारा: Stylianou, E, और अन्य
प्रकाशित: (2019)

Vaccines for tuberculosis
द्वारा: McShane, H
प्रकाशित: (2013)

Cholera toxin enhances vaccine-induced protection against Mycobacterium tuberculosis challenge in mice
द्वारा: Griffiths, K, और अन्य
प्रकाशित: (2013)

A human challenge model for Mycobacterium tuberculosis using Mycobacterium bovis bacille Calmette-Guérin
द्वारा: Minassian, A, और अन्य
प्रकाशित: (2012)

A human challenge model for Mycobacterium tuberculosis using Mycobacterium bovis bacille Calmette-Guerin.
द्वारा: Minassian, A, और अन्य
प्रकाशित: (2012)

Optimisation of a human BCG challenge model
द्वारा: Wilkie, M, और अन्य
प्रकाशित: (2015)

Development of a BCG challenge model for the testing of vaccine candidates against tuberculosis in cattle.
द्वारा: Villarreal-Ramos, B, और अन्य
प्रकाशित: (2014)

Development of a BCG challenge model for the testing of vaccine candidates against tuberculosis in cattle
द्वारा: Villarreal-Ramos, B, और अन्य
प्रकाशित: (2014)

Tuberculosis vaccines: beyond bacille Calmette–Guérin
द्वारा: McShane, H
प्रकाशित: (2011)

Tuberculosis vaccines: Beyond bacilli Calmette-Guérin
द्वारा: McShane, H
प्रकाशित: (2011)

Effects of MVA85A vaccine on tuberculosis challenge in animals: systematic review
द्वारा: Mcshane, H, और अन्य
प्रकाशित: (2016)

The VALIDATE network: accelerating vaccine development for tuberculosis, leishmaniasis, melioidosis and leprosy
द्वारा: Vermaak, S, और अन्य
प्रकाशित: (2023)

Progress and challenges in TB vaccine development
द्वारा: Voss, G, और अन्य
प्रकाशित: (2018)

Improving tuberculosis vaccine trial efficiency: a tough nut to crack
द्वारा: McShane, H
प्रकाशित: (2023)

Preclinical development of an in vivo BCG challenge model for testing candidate TB vaccine efficacy.
द्वारा: Minassian, A, और अन्य
प्रकाशित: (2011)

Local pulmonary immunological biomarkers in tuberculosis
द्वारा: Morrison, H, और अन्य
प्रकाशित: (2021)

SARS-CoV-2 human challenge studies - establishing the model during an evolving pandemic
द्वारा: Rapeport, G, और अन्य
प्रकाशित: (2021)

Why don’t we have an effective tuberculosis vaccine yet?
द्वारा: Davenne, T, और अन्य
प्रकाशित: (2016)

Diagnostic tests for Alzheimer's disease: Rationale, methodology, and challenges
द्वारा: Ritchie, C, और अन्य
प्रकाशित: (2010)

Knee Tuberculosis: a challenge in diagnosis and treatment
द्वारा: Muhammad Wafiuddin Ahmad, और अन्य
प्रकाशित: (2021)

Establishment of an aerosol challenge model of tuberculosis in rhesus macaques and an evaluation of endpoints for vaccine testing.
द्वारा: Sharpe, SA, और अन्य
प्रकाशित: (2010)

Clinical testing of tuberculosis vaccine candidates
द्वारा: Hatherill, M, और अन्य
प्रकाशित: (2016)

Antibodies and tuberculosis
द्वारा: Jacobs, A, और अन्य
प्रकाशित: (2016)

Current approaches toward identifying a correlate of immune protection from tuberculosis
द्वारा: Satti, I, और अन्य
प्रकाशित: (2018)

Th1/Th17 cell induction following vaccination with the novel tuberculosis vaccine MVA85A and their role in Mycobacterium tuberculosis challenge
द्वारा: Griffiths, K, और अन्य
प्रकाशित: (2011)

Optimization of a human bacille Calmette-Guerin challenge model: a tool to evaluate antimycobacterial immunity
द्वारा: Minhinnick, A, और अन्य
प्रकाशित: (2015)

Replacing, reducing and refining the use of animals in tuberculosis vaccine 1 research
द्वारा: Tanner, R, और अन्य
प्रकाशित: (2016)

Modelling challenges in context: lessons from malaria, HIV, and tuberculosis
द्वारा: Childs, L, और अन्य
प्रकाशित: (2015)

Tuberculosis vaccines in the era of Covid-19 - what is taking us so long?
द्वारा: Dockrell, HM, और अन्य
प्रकाशित: (2022)

Pharmacological Management of Tuberculosis, Challenges, and Potential Strategies
द्वारा: Xin, Bernadette Jie Tune, और अन्य
प्रकाशित: (2024)

Evaluation of a human BCG challenge model to assess antimycobacterial immunity induced by BCG and a candidate tuberculosis vaccine, MVA85A, alone and in combination.
द्वारा: Harris, SA, और अन्य
प्रकाशित: (2014)