The crystal structure of IgE Fc reveals an asymmetrically bent conformation.

The crystal structure of IgE Fc reveals an asymmetrically bent conformation.

The distinguishing structural feature of immunoglobulin E (IgE), the antibody responsible for allergic hypersensitivity, is the C epsilon 2 domain pair that replaces the hinge region of IgG. The crystal structure of the IgE Fc (constant fragment) at a 2.6-A resolution has revealed these domains. The...

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Huvudupphovsmän: Wan, T, Beavil, R, Fabiane, S, Beavil, A, Sohi, M, Keown, M, Young, R, Henry, A, Owens, R, Gould, H, Sutton, B
Materialtyp: Journal article
Språk:English
Publicerad: 2002

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