Breast cancer risk in male twins: joint analyses of four twin cohorts in Denmark, Finland, Sweden and the United States.
To test the hypothesis that in utero exposure to high levels of oestrogen increases the risk of male breast cancer, we followed 115 235 male twins for more than 3.5 million person-years at risk. We observed 11 cases of male breast cancer versus 16.16 expected based on national rates (standardized ra...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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| _version_ | 1797077791217287168 |
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| author | Whiteman, D Murphy, M Verkasalo, P Page, W Floderus, B Skytthe, A Holm, N |
| author_facet | Whiteman, D Murphy, M Verkasalo, P Page, W Floderus, B Skytthe, A Holm, N |
| author_sort | Whiteman, D |
| collection | OXFORD |
| description | To test the hypothesis that in utero exposure to high levels of oestrogen increases the risk of male breast cancer, we followed 115 235 male twins for more than 3.5 million person-years at risk. We observed 11 cases of male breast cancer versus 16.16 expected based on national rates (standardized rate ratio 0.68, 95% confidence interval 0.34-1.22) and conclude that any adverse influence of in utero oestrogen exposure is likely to be small. |
| first_indexed | 2024-03-07T00:23:04Z |
| format | Journal article |
| id | oxford-uuid:7d337ca9-80f2-432c-8e60-8fce5994d894 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:23:04Z |
| publishDate | 2000 |
| record_format | dspace |
| spelling | oxford-uuid:7d337ca9-80f2-432c-8e60-8fce5994d8942022-03-26T21:02:07ZBreast cancer risk in male twins: joint analyses of four twin cohorts in Denmark, Finland, Sweden and the United States.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7d337ca9-80f2-432c-8e60-8fce5994d894EnglishSymplectic Elements at Oxford2000Whiteman, DMurphy, MVerkasalo, PPage, WFloderus, BSkytthe, AHolm, NTo test the hypothesis that in utero exposure to high levels of oestrogen increases the risk of male breast cancer, we followed 115 235 male twins for more than 3.5 million person-years at risk. We observed 11 cases of male breast cancer versus 16.16 expected based on national rates (standardized rate ratio 0.68, 95% confidence interval 0.34-1.22) and conclude that any adverse influence of in utero oestrogen exposure is likely to be small. |
| spellingShingle | Whiteman, D Murphy, M Verkasalo, P Page, W Floderus, B Skytthe, A Holm, N Breast cancer risk in male twins: joint analyses of four twin cohorts in Denmark, Finland, Sweden and the United States. |
| title | Breast cancer risk in male twins: joint analyses of four twin cohorts in Denmark, Finland, Sweden and the United States. |
| title_full | Breast cancer risk in male twins: joint analyses of four twin cohorts in Denmark, Finland, Sweden and the United States. |
| title_fullStr | Breast cancer risk in male twins: joint analyses of four twin cohorts in Denmark, Finland, Sweden and the United States. |
| title_full_unstemmed | Breast cancer risk in male twins: joint analyses of four twin cohorts in Denmark, Finland, Sweden and the United States. |
| title_short | Breast cancer risk in male twins: joint analyses of four twin cohorts in Denmark, Finland, Sweden and the United States. |
| title_sort | breast cancer risk in male twins joint analyses of four twin cohorts in denmark finland sweden and the united states |
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