Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism.
Linkage studies have provided evidence that one or more loci on chromosome 9q influence Alzheimer disease (AD). The gene encoding the ATP-binding cassette A1 transporter (ABCA1) resides within proximity of previously identified linkage peaks and represents a plausible biological candidate for AD due...
Main Authors: | Katzov, H, Chalmers, K, Palmgren, J, Andreasen, N, Johansson, B, Cairns, N, Gatz, M, Wilcock, G, Love, S, Pedersen, N, Brookes, A, Blennow, K, Kehoe, P, Prince, J |
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Format: | Journal article |
Language: | English |
Published: |
2004
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