Expression of hypoxia-inducible factors is correlated with the presence of a fibrotic focus and angiogenesis in pancreatic ductal adenocarcinomas.

Expression of hypoxia-inducible factors is correlated with the presence of a fibrotic focus and angiogenesis in pancreatic ductal adenocarcinomas.

AIMS: To study the expression of hypoxia-regulated markers in pancreatic ductal adenocarcinomas (PA) in relationship to the presence of a fibrotic focus, angiogenesis quantification and clinical outcome. METHODS AND RESULTS: The expression of hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, carbon...

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Bibliographic Details
Main Authors: Couvelard, A, O'Toole, D, Leek, R, Turley, H, Sauvanet, A, Degott, C, Ruszniewski, P, Belghiti, J, Harris, A, Gatter, K, Pezzella, F
Format: Journal article
Language:English
Published: 2005

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