Cancer cell killing by target antigen engagement with engineered complementary intracellular antibody single domains fused to pro-caspase3

Cancer cell killing by target antigen engagement with engineered complementary intracellular antibody single domains fused to pro-caspase3

<p>Many tumour causing proteins, such as those expressed after chromosomal translocations or from point mutations, are intracellular and are not enzymes <em>per se</em> amenable to conventional drug targeting. We previously demonstrated an approach (<u>A</u>ntibody-anti...

Bibliografske podrobnosti
Main Authors:	Chambers, J, Brend, T, Rabbitts, T
Format:	Journal article
Jezik:	English
Izdano:	Nature Research 2019

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