Differential thermostability and response to cystic fibrosis transmembrane conductance regulator (CFTR) potentiators of human and mouse F508del-CFTR

Differential thermostability and response to cystic fibrosis transmembrane conductance regulator (CFTR) potentiators of human and mouse F508del-CFTR

Cross-species comparative studies have highlighted differences between human and mouse cystic fibrosis transmembrane conductance regulator (CFTR), the epithelial Cl− channel defective in cystic fibrosis (CF). Here, we compare the impact of the most common CF mutation F508del on the function of human...

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Detalles Bibliográficos
Autores principales:	Bose, S, Bijvelds, M, Wang, Y, Liu, J, Cai, Z, Bot, A, De Jonge, H, Sheppard, D
Formato:	Journal article
Lenguaje:	English
Publicado:	American Physiological Society 2019

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