Inorganic pyrophosphate in plasma, urine, and synovial fluid of patients with pyrophosphate arthropathy (chondrocalcinosis or pseudogout).
The concentration of inorganic pyrophosphate (I.P.P.) has been determined in the plasma, urine, and synovial fluid of patients with pyrophosphate arthropathy (chondrocalcinosis articularis or pseudogout). The concentrations of I.P.P. in plasma and urine were normal in patients with pyrophosphate art...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
1970
|
| Summary: | The concentration of inorganic pyrophosphate (I.P.P.) has been determined in the plasma, urine, and synovial fluid of patients with pyrophosphate arthropathy (chondrocalcinosis articularis or pseudogout). The concentrations of I.P.P. in plasma and urine were normal in patients with pyrophosphate arthropathy. In contrast, the concentrations in synovial fluid were higher in patients with pyrophosphate arthropathy (0·41-3·76 μg. I.P.P. per ml.) than in patients with joint effusions due to other causes (0·06-0·32 μg. I.P.P. per ml.). The concentrations of calcium and alkaline phosphatase were lower in the synovial fluid of patients than of controls. The disturbance in I.P.P. metabolism in pyrophosphate arthropathy seems to be a local rather than generalised phenomenon. © 1970. |
|---|