How many specific B cells are needed to protect against a virus?
The size of the Ab repertoire has been estimated to comprise theoretically somewhere between > 10(10) and approximately 10(4) specificities, dependent on the criteria used. In an attempt to estimate the anti-viral protective Ab repertoire of the mouse the B cell and Ab-forming cell (AFC) freq...
Hauptverfasser: | Bachmann, M, Kündig, T, Kalberer, C, Hengartner, H, Zinkernagel, R |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
1994
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