The role of the transcription factor BRN2 in melanoma

The role of the transcription factor BRN2 in melanoma

<p>Expression of the POU-domain transcription factor BRN2 is crucial for the developing brain and drives proliferation and invasiveness in cancers of neural crest origin including melanoma. However, our understanding of BRN2 function and how its behaviour is modulated remains incomplete. We th...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoir:	Herbert, K
Rannpháirtithe:	Goding, C
Formáid:	Tráchtas
Foilsithe / Cruthaithe:	2018

Míreanna comhchosúla

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BRN2 phosphorylation regulates melanoblast migration and proliferation through PAX3 and MITF-M
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Phosphorylation of BRN2 modulates its interaction with the Pax3 promoter to control melanocyte migration and proliferation.
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Crystal structure of 2-bromobenzoic acid hydrazide, C7H7BrN2O
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Crystal structure of N'-(5-bromo-2-hydroxy-3-methoxybenzylidene)-2- methoxybenzohydrazide monohydrate, C16H15BrN2O4·H2O, C16H17BrN2O5
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Crystal structure of 3-(2-bromophenyl)-1,1-dimethylthiourea, C9H11BrN2S
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The transcription network regulating melanocyte development and melanoma.
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