The role of the transcription factor BRN2 in melanoma
<p>Expression of the POU-domain transcription factor BRN2 is crucial for the developing brain and drives proliferation and invasiveness in cancers of neural crest origin including melanoma. However, our understanding of BRN2 function and how its behaviour is modulated remains incomplete. We th...
Үндсэн зохиолч: | Herbert, K |
---|---|
Бусад зохиолчид: | Goding, C |
Формат: | Дипломын ажил |
Хэвлэсэн: |
2018
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Ижил төстэй зүйлс
Ижил төстэй зүйлс
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The Brn-2 transcription factor links activated BRAF to melanoma proliferation.
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Regulation of MITF and Brn2 in melanoma
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Targeting Neuronal Transcription Factor BRN2 in Neuroendocrine Tumors
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The POU domain transcription factor Brn-2: elevated expression in malignant melanoma and regulation of melanocyte-specific gene expression.
-н: Eisen, T, зэрэг
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Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor-negative melanoma cells.
-н: Goodall, J, зэрэг
Хэвлэсэн: (2008)