High frequencies of alpha-thalassaemia are the result of natural selection by malaria.
The frequency of alpha+-thalassaemia, but not other unlinked DNA polymorphisms, exhibits an altitude- and latitude-dependent correlation with malaria endemicity throughout Melanesia, supporting the hypothesis that protection against this parasitic disease is the major factor responsible for the high...
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Bibliographic Details
| Main Authors: |
Flint, J,
Hill, A,
Bowden, D,
Oppenheimer, S,
Sill, P,
Serjeantson, S,
Bana-Koiri, J,
Bhatia, K,
Alpers, M,
Boyce, A |
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| Format: | Journal article
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| Language: | English |
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| Published: |
1986
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