Human tumour clonality assessment--flawed but necessary.

One of the premises of the somatic mutation theory of carcinogenesis is that tumours are clonal lesions derived from a single mutated stem cell progenitor. This theory spawned a proliferation of clonality studies, using a variety of different molecular markers to try to determine tumour clonality in...

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Hlavní autoři: Leedham, S, Wright, N
Médium: Journal article
Jazyk:English
Vydáno: 2008