Human tumour clonality assessment--flawed but necessary.
One of the premises of the somatic mutation theory of carcinogenesis is that tumours are clonal lesions derived from a single mutated stem cell progenitor. This theory spawned a proliferation of clonality studies, using a variety of different molecular markers to try to determine tumour clonality in...
Κύριοι συγγραφείς: | Leedham, S, Wright, N |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2008
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Παρόμοια τεκμήρια
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The clonal origin of human tumours: is familial adenomatous polyposis (FAP) different?
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Methylation and Clonality of Human Colonic Crypts
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Mapping clonality in individual glands in human Barrett's esophagus
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Έκδοση: (2007) -
Mapping clonality in individual glands from human Barrett's oesophagus
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Έκδοση: (2007) -
Patch size in the human colon confounds the assessment of tumour clonality using X chromosome-linked markers
ανά: Novelli, M, κ.ά.
Έκδοση: (2002)