Human tumour clonality assessment--flawed but necessary.

Human tumour clonality assessment--flawed but necessary.

One of the premises of the somatic mutation theory of carcinogenesis is that tumours are clonal lesions derived from a single mutated stem cell progenitor. This theory spawned a proliferation of clonality studies, using a variety of different molecular markers to try to determine tumour clonality in...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Leedham, S, Wright, N
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2008

समान संसाधन

The clonal origin of human tumours: is familial adenomatous polyposis (FAP) different?
द्वारा: Leedham, S, और अन्य
प्रकाशित: (2006)

Methylation and Clonality of Human Colonic Crypts
द्वारा: Graham, T, और अन्य
प्रकाशित: (2009)

Mapping clonality in individual glands in human Barrett's esophagus
द्वारा: Leedham, S, और अन्य
प्रकाशित: (2007)

Mapping clonality in individual glands from human Barrett's oesophagus
द्वारा: Leedham, S, और अन्य
प्रकाशित: (2007)

Patch size in the human colon confounds the assessment of tumour clonality using X chromosome-linked markers
द्वारा: Novelli, M, और अन्य
प्रकाशित: (2002)

Patch size in the human colon confounds the assessment of tumour clonality using X chromosome-linked markers.
द्वारा: Novelli, M, और अन्य
प्रकाशित: (2002)

Expansion of a mutated clone: from stem cell to tumour.
द्वारा: Leedham, S, और अन्य
प्रकाशित: (2008)

The evidence base of proton pump inhibitor chemopreventative agents in Barrett's esophagus--the good, the bad, and the flawed!
द्वारा: Leedham, S, और अन्य
प्रकाशित: (2007)

The Clonal Origins of Dysplasia from Metaplasia in the Human Stomach
द्वारा: Gutierrez, L, और अन्य
प्रकाशित: (2009)

Using somatic APC mutations as clonal markers in colonic polyps
द्वारा: Leedham, S, और अन्य
प्रकाशित: (2007)

Clonal expansion in the human gut: mitochondrial DNA mutations show us the way.
द्वारा: McDonald, SA, और अन्य
प्रकाशित: (2006)

Monoclonal conversion in human gastric glands gives insights into stem cell and clonal architecture
द्वारा: McDonald, S, और अन्य
प्रकाशित: (2005)

Clonality assessment and clonal ordering of individual neoplastic crypts shows polyclonality of colorectal adenomas.
द्वारा: Thirlwell, C, और अन्य
प्रकाशित: (2010)

Using somatic APC mutations as clonal markers to demonstrate polyclonality in colonic polyps
द्वारा: Leedham, S, और अन्य
प्रकाशित: (2007)

Clonality, founder mutations, and field cancerization in human ulcerative colitis-associated neoplasia.
द्वारा: Leedham, S, और अन्य
प्रकाशित: (2009)

The fixation of mutations and clonal expansion in intestinal metaplasia: Field cancerisation in the human stomach
द्वारा: McDonald, S, और अन्य
प्रकाशित: (2008)

FLAWED /
द्वारा: Ahern, Cecelia, 1981-, author 319498
प्रकाशित: (2016)

Noise: A Flaw in Human Judgment
द्वारा: Umar Sadeeq
प्रकाशित: (2023-06-01)

Noise: A Flaw in Human Judgement /
द्वारा: Daniel, Kahneman, author, और अन्य
प्रकाशित: (2021)

THE CLONAL PROGRESSION OF BARRETT'S OESOPHAGUS TO OESOPHAGEAL ADENOCARCINOMA
द्वारा: Khan, S, और अन्य
प्रकाशित: (2012)

Clonal diversification and histogenesis of malignant germ cell tumours
द्वारा: Thomas R. W. Oliver, और अन्य
प्रकाशित: (2022-08-01)

METHODS FOR TRACING CRYPT STEM CELLS ANCESTRY AND CLONAL ARCHITECTURE USING CPG ISLAND METHYLATION AND MITOCHONDRIAL DNA MUTATIONS
द्वारा: Graham, T, और अन्य
प्रकाशित: (2009)

Perfect IMPERFECTIONS : HONOURING FLAWS AS HUMAN NATURE /
द्वारा: Ummu Ahmadain, author 655822
प्रकाशित: (2024)

The clonal origins of dysplasia from intestinal metaplasia in the human stomach.
द्वारा: Gutierrez-Gonzalez, L, और अन्य
प्रकाशित: (2011)

From gene mutations to tumours--stem cells in gastrointestinal carcinogenesis.
द्वारा: Leedham, S, और अन्य
प्रकाशित: (2005)

SSL-TLS security flaws : the CRIME compression attack security flaws
द्वारा: Peh, Kenneth Hong Wei
प्रकाशित: (2020)

HUMAN SMALL INTESTINAL CRYPTS ARE CLONAL, CONTAIN MULTIPLE STEM CELLS AND MUTATED CRYPTS DIVIDE BY FISSION
द्वारा: Gutierrez-Gonzalez, L, और अन्य
प्रकाशित: (2009)

When, why and how tumour clonal diversity predicts survival
द्वारा: Robert Noble, और अन्य
प्रकाशित: (2020-08-01)

Transducers for ultrasonic flaw detection /
द्वारा: 193444 Bindal, V. N.
प्रकाशित: (1999)

Mesenchymal/stromal stem cells: necessary factors in tumour progression
द्वारा: Xinyu Li, और अन्य
प्रकाशित: (2022-07-01)

Common Flaws in Running Human Evaluation Experiments in NLP
द्वारा: Craig Thomson, और अन्य
प्रकाशित: (2024-07-01)

Flawed validation of FRAX
द्वारा: Collins, G, और अन्य
प्रकाशित: (2016)

A flawed trial
द्वारा: Abd Razak, Dzulkifli
प्रकाशित: (2007)

Flaws of the individual or the system?
द्वारा: Haleem, Irm
प्रकाशित: (2020)

Textual and language flaws
द्वारा: Isabel Kareli León Pérez, और अन्य
प्रकाशित: (2006-01-01)

Flaw growth and fracture
द्वारा: National Symposium on Fracture Mechanics (10th : 1976 : Philadelphia, Pa.), और अन्य
प्रकाशित: (1977)

Flawed assets clauses
द्वारा: Gullifer, L
प्रकाशित: (2017)

Penetrant flaw detection
द्वारा: 8096 British Standards Institution
प्रकाशित: (1984)

Flawed analysis of an intentional human dosing study and its impact on chlorpyrifos risk assessments
द्वारा: Lianne Sheppard, और अन्य
प्रकाशित: (2020-10-01)

Fracture toughness, surface flaw sizes and flaw densities in Al2O3
द्वारा: Franco, A, और अन्य
प्रकाशित: (1997)