Molecular analysis of the interaction of the snake venom rhodocytin with the platelet receptor CLEC-2.
The Malayan pit viper, Calloselasma rhodostoma, produces a potent venom toxin, rhodocytin (aggretin) which causes platelet aggregation. Rhodocytin is a ligand for the receptor CLEC-2 on the surface of platelets. The interaction of these two molecules initiates a signaling pathway which results in pl...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2011
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