Volumetric cortical loss in sporadic and familial amyotrophic lateral sclerosis.
Patients homozygous for the D90A mutation of the SOD1 gene (homD90A) demonstrate markedly slower progression of disease than those patients with sporadic ALS (SALS). PET studies have demonstrated a different cortical vulnerability in the two groups, reflected also in neurophysiological studies showi...
Main Authors: | Turner, M, Hammers, A, Allsop, J, Al-Chalabi, A, Shaw, C, Brooks, D, Leigh, P, Andersen, P |
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格式: | Journal article |
语言: | English |
出版: |
2007
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