Volumetric cortical loss in sporadic and familial amyotrophic lateral sclerosis.
Patients homozygous for the D90A mutation of the SOD1 gene (homD90A) demonstrate markedly slower progression of disease than those patients with sporadic ALS (SALS). PET studies have demonstrated a different cortical vulnerability in the two groups, reflected also in neurophysiological studies showi...
Κύριοι συγγραφείς: | Turner, M, Hammers, A, Allsop, J, Al-Chalabi, A, Shaw, C, Brooks, D, Leigh, P, Andersen, P |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2007
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Παρόμοια τεκμήρια
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Cortical involvement in four cases of primary lateral sclerosis using [(11)C]-flumazenil PET.
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Prognostic modelling of therapeutic interventions in amyotrophic lateral sclerosis.
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Abnormal cortical excitability in sporadic but not homozygous D90A SOD1 ALS.
ανά: Turner, M, κ.ά.
Έκδοση: (2005)