What drives recombination hotspots to repeat DNA in humans?

What drives recombination hotspots to repeat DNA in humans?

Recombination between homologous, but non-allelic, stretches of DNA such as gene families, segmental duplications and repeat elements is an important source of mutation. In humans, recent studies have identified short DNA motifs that both determine the location of 40 per cent of meiotic cross-over h...

书目详细资料
主要作者:	McVean, G
格式:	Journal article
语言:	English
出版:	2010

相似书籍

Recombination rate estimation in the presence of hotspots.
由: Auton, A, et al.
出版: (2007)

Recombination Rates, their local variation and the estimated number of hotspots in the human genome.
由: Stumpf, M, et al.
出版: (2003)

A fine-scale map of recombination rates and hotspots across the human genome.
由: Myers, S, et al.
出版: (2005)

Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination.
由: Myers, S, et al.
出版: (2010)

Recombination hotspots and population structure in Plasmodium falciparum.
由: Mu, J, et al.
出版: (2005)

Stable recombination hotspots in birds
由: Singhal, S, et al.
出版: (2015)

Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination
由: Myers, Simon, et al.
出版: (2010)

Evolutionary genetics: what is driving male mutation?
由: McVean, G
出版: (2000)

Recombination hotspots and population structure in Plasmodium falciparum.
由: Mu, J, et al.
出版: (2005)

Centromeres as universal hotspots of DNA breakage, driving RAD51-mediated recombination during quiescence
由: Saayman, X, et al.
出版: (2023)

Estimating recombination rates from genetic variation in humans.
由: Auton, A, et al.
出版: (2012)

Human polymorphism around recombination hotspots.
由: Spencer, C
出版: (2006)

Molecular mechanisms of recombination hotspots in humans
由: Noor, N
出版: (2013)

Linkage Disequilibrium, Recombination and Selection
由: McVean, G
出版: (2008)

High recombination rates and hotspots in a Plasmodium falciparum genetic cross.
由: Jiang, H, et al.
出版: (2011)

Mobile elements drive recombination hotspots in the core genome of Staphylococcus aureus
由: Everitt, R, et al.
出版: (2014)

Mobile elements drive recombination hotspots in the core genome of Staphylococcus aureus.
由: Everitt, R, et al.
出版: (2014)

Predicting DNA sequence motifs of recombination hotspots by integrative visualization and analysis
由: Khil, Pavel P., et al.
出版: (2013)

Estimating diversifying selection and functional constraint in the presence of recombination.
由: Wilson, D, et al.
出版: (2006)

Estimating recombination rates from population-genetic data.
由: Stumpf, M, et al.
出版: (2003)

The distribution and causes of meiotic recombination in the human genome.
由: Myers, S, et al.
出版: (2006)

A web-server for analysis of DNA sequence motifs associated with genomic recombination hotspots
由: Hoang, Quoc Bao
出版: (2014)

The influence of recombination on human genetic diversity.
由: Spencer, C, et al.
出版: (2006)

The influence of recombination on human genetic diversity.
由: Spencer, C, et al.
出版: (2006)

A common sequence motif associated with recombination hot spots and genome instability in humans.
由: Myers, S, et al.
出版: (2008)

A common sequence motif associated with recombination hot spots and genome instability in humans.
由: Myers, S, et al.
出版: (2008)

What do patterns of genetic variability reveal about mitochondrial recombination?
由: Mcvean, G
出版: (2001)

Integration of genomic and epigenomic features to predict meiotic recombination hotspots in human and mouse
由: Przytycka, Teresa M., et al.
出版: (2013)

A coalescent-based method for detecting and estimating recombination from gene sequences.
由: McVean, G, et al.
出版: (2002)

Prediction of trans-regulators of recombination hotspots in mouse genome
由: Przytycka, Teresa M., et al.
出版: (2013)

Live hot, die young: transmission distortion in recombination hotspots.
由: Coop, G, et al.
出版: (2007)

Live hot, die young: Transmission distortion in recombination hotspots
由: Coop, G, et al.
出版: (2007)

LDsplit : screening for cis-regulatory motifs stimulating meiotic recombination hotspots by analysis of DNA sequence polymorphisms
由: Przytycka, Teresa M., et al.
出版: (2014)

Human genome sequence variation and the influence of gene history, mutation and recombination.
由: Reich, D, et al.
出版: (2002)

Scanning the human genome for signals of selection.
由: McVean, G, et al.
出版: (2006)

Epigenetic functions enriched in transcription factors binding to mouse recombination hotspots
由: Wu, Min, et al.
出版: (2013)

A structured ancestral population for the evolution of modern humans.
由: Harding, R, et al.
出版: (2004)

LDSplitDB : a database for studies of meiotic recombination hotspots in MHC using human genomic data
由: Guo, Jing, et al.
出版: (2018)

Finding trans-regulatory genes and protein complexes modulating meiotic recombination hotspots of human, mouse and yeast
由: Wu, Min, et al.
出版: (2014)

Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum.
由: Miles, A, et al.
出版: (2016)