Jaspine B (pachastrissamine) and 2-epi-jaspine B: synthesis and structural assignment

Jaspine B (pachastrissamine), which was isolated in 2002, is a naturally occurring anhydrophytosphingosine which displays potent biological activity, and as such has attracted much attention from synthetic chemists in recent years, with 14 syntheses reported to date. This review delineates the isola...

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Detalhes bibliográficos
Principais autores: Abraham, E, Davies, S, Roberts, P, Russell, A, Thomson, J
Formato: Journal article
Idioma:English
Publicado em: 2008
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author Abraham, E
Davies, S
Roberts, P
Russell, A
Thomson, J
author_facet Abraham, E
Davies, S
Roberts, P
Russell, A
Thomson, J
author_sort Abraham, E
collection OXFORD
description Jaspine B (pachastrissamine), which was isolated in 2002, is a naturally occurring anhydrophytosphingosine which displays potent biological activity, and as such has attracted much attention from synthetic chemists in recent years, with 14 syntheses reported to date. This review delineates the isolation of jaspine B, and laboratory total syntheses of jaspine B, 2-epi-jaspine B and analogues, which serves to confirm their structure and stereochemistry. © 2008 Elsevier Ltd. All rights reserved.
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spelling oxford-uuid:7dcac3e5-919c-4e1b-b490-0b628d6c54242022-03-26T21:05:52ZJaspine B (pachastrissamine) and 2-epi-jaspine B: synthesis and structural assignmentJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7dcac3e5-919c-4e1b-b490-0b628d6c5424EnglishSymplectic Elements at Oxford2008Abraham, EDavies, SRoberts, PRussell, AThomson, JJaspine B (pachastrissamine), which was isolated in 2002, is a naturally occurring anhydrophytosphingosine which displays potent biological activity, and as such has attracted much attention from synthetic chemists in recent years, with 14 syntheses reported to date. This review delineates the isolation of jaspine B, and laboratory total syntheses of jaspine B, 2-epi-jaspine B and analogues, which serves to confirm their structure and stereochemistry. © 2008 Elsevier Ltd. All rights reserved.
spellingShingle Abraham, E
Davies, S
Roberts, P
Russell, A
Thomson, J
Jaspine B (pachastrissamine) and 2-epi-jaspine B: synthesis and structural assignment
title Jaspine B (pachastrissamine) and 2-epi-jaspine B: synthesis and structural assignment
title_full Jaspine B (pachastrissamine) and 2-epi-jaspine B: synthesis and structural assignment
title_fullStr Jaspine B (pachastrissamine) and 2-epi-jaspine B: synthesis and structural assignment
title_full_unstemmed Jaspine B (pachastrissamine) and 2-epi-jaspine B: synthesis and structural assignment
title_short Jaspine B (pachastrissamine) and 2-epi-jaspine B: synthesis and structural assignment
title_sort jaspine b pachastrissamine and 2 epi jaspine b synthesis and structural assignment
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AT daviess jaspinebpachastrissamineand2epijaspinebsynthesisandstructuralassignment
AT robertsp jaspinebpachastrissamineand2epijaspinebsynthesisandstructuralassignment
AT russella jaspinebpachastrissamineand2epijaspinebsynthesisandstructuralassignment
AT thomsonj jaspinebpachastrissamineand2epijaspinebsynthesisandstructuralassignment