Morbidity and associated factors of depressive disorder in patients with Parkinson's disease
Parkinson's disease (PD) is a progressive, neurodegenerative disorder and is commonly comorbid with depression. The aim of this cross-sectional study was to assess morbidity and associated factors of depression in patients with PD. In total, 181 patients with PD were enrolled and assessed using...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
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Lippincott, Williams & Wilkins
2022
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_version_ | 1797109044935131136 |
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author | Lee, Y Chiou, Y-J Chang, Y-Y Hung, C-F Chen, Y-F Lin, T-K Wang, L-J |
author_facet | Lee, Y Chiou, Y-J Chang, Y-Y Hung, C-F Chen, Y-F Lin, T-K Wang, L-J |
author_sort | Lee, Y |
collection | OXFORD |
description | Parkinson's disease (PD) is a progressive, neurodegenerative disorder and is commonly comorbid with depression. The aim of this cross-sectional study was to assess morbidity and associated factors of depression in patients with PD. In total, 181 patients with PD were enrolled and assessed using the Mini-International Neuropsychiatric Interview. Of the sample, 51% had at least one psychiatric diagnosis. The most prevalent psychiatric disorder was depressive disorder (27.6%), followed by rapid eye movement sleep behavior disorder (9.9%), insomnia disorder (8.8%), and adjustment disorder (2.8%). Severity of anxiety, suicide risk, and anxiolytics/hypnotics use were factors associated with depressive disorder in PD patients. Furthermore, severity of anxiety was significantly linked with suicide risk. We suggest that use of a standardized structured interview for early detection of depression in PD patients is crucial. Anxiety, anxiolytics/hypnotics use, depression, and suicide risks are interrelated and warrant clinical concerns regarding PD patients. |
first_indexed | 2024-03-07T07:36:33Z |
format | Journal article |
id | oxford-uuid:7dcfdf9d-3b6b-400d-b1d6-68dceeb68c6b |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T07:36:33Z |
publishDate | 2022 |
publisher | Lippincott, Williams & Wilkins |
record_format | dspace |
spelling | oxford-uuid:7dcfdf9d-3b6b-400d-b1d6-68dceeb68c6b2023-03-10T12:23:15ZMorbidity and associated factors of depressive disorder in patients with Parkinson's diseaseJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7dcfdf9d-3b6b-400d-b1d6-68dceeb68c6bEnglishSymplectic ElementsLippincott, Williams & Wilkins2022Lee, YChiou, Y-JChang, Y-YHung, C-FChen, Y-FLin, T-KWang, L-JParkinson's disease (PD) is a progressive, neurodegenerative disorder and is commonly comorbid with depression. The aim of this cross-sectional study was to assess morbidity and associated factors of depression in patients with PD. In total, 181 patients with PD were enrolled and assessed using the Mini-International Neuropsychiatric Interview. Of the sample, 51% had at least one psychiatric diagnosis. The most prevalent psychiatric disorder was depressive disorder (27.6%), followed by rapid eye movement sleep behavior disorder (9.9%), insomnia disorder (8.8%), and adjustment disorder (2.8%). Severity of anxiety, suicide risk, and anxiolytics/hypnotics use were factors associated with depressive disorder in PD patients. Furthermore, severity of anxiety was significantly linked with suicide risk. We suggest that use of a standardized structured interview for early detection of depression in PD patients is crucial. Anxiety, anxiolytics/hypnotics use, depression, and suicide risks are interrelated and warrant clinical concerns regarding PD patients. |
spellingShingle | Lee, Y Chiou, Y-J Chang, Y-Y Hung, C-F Chen, Y-F Lin, T-K Wang, L-J Morbidity and associated factors of depressive disorder in patients with Parkinson's disease |
title | Morbidity and associated factors of depressive disorder in patients with Parkinson's disease |
title_full | Morbidity and associated factors of depressive disorder in patients with Parkinson's disease |
title_fullStr | Morbidity and associated factors of depressive disorder in patients with Parkinson's disease |
title_full_unstemmed | Morbidity and associated factors of depressive disorder in patients with Parkinson's disease |
title_short | Morbidity and associated factors of depressive disorder in patients with Parkinson's disease |
title_sort | morbidity and associated factors of depressive disorder in patients with parkinson s disease |
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