Morbidity and associated factors of depressive disorder in patients with Parkinson's disease
Parkinson's disease (PD) is a progressive, neurodegenerative disorder and is commonly comorbid with depression. The aim of this cross-sectional study was to assess morbidity and associated factors of depression in patients with PD. In total, 181 patients with PD were enrolled and assessed using...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
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Lippincott, Williams & Wilkins
2022
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| _version_ | 1797109044935131136 |
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| author | Lee, Y Chiou, Y-J Chang, Y-Y Hung, C-F Chen, Y-F Lin, T-K Wang, L-J |
| author_facet | Lee, Y Chiou, Y-J Chang, Y-Y Hung, C-F Chen, Y-F Lin, T-K Wang, L-J |
| author_sort | Lee, Y |
| collection | OXFORD |
| description | Parkinson's disease (PD) is a progressive, neurodegenerative disorder and is commonly comorbid with depression. The aim of this cross-sectional study was to assess morbidity and associated factors of depression in patients with PD. In total, 181 patients with PD were enrolled and assessed using the Mini-International Neuropsychiatric Interview. Of the sample, 51% had at least one psychiatric diagnosis. The most prevalent psychiatric disorder was depressive disorder (27.6%), followed by rapid eye movement sleep behavior disorder (9.9%), insomnia disorder (8.8%), and adjustment disorder (2.8%). Severity of anxiety, suicide risk, and anxiolytics/hypnotics use were factors associated with depressive disorder in PD patients. Furthermore, severity of anxiety was significantly linked with suicide risk. We suggest that use of a standardized structured interview for early detection of depression in PD patients is crucial. Anxiety, anxiolytics/hypnotics use, depression, and suicide risks are interrelated and warrant clinical concerns regarding PD patients. |
| first_indexed | 2024-03-07T07:36:33Z |
| format | Journal article |
| id | oxford-uuid:7dcfdf9d-3b6b-400d-b1d6-68dceeb68c6b |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:36:33Z |
| publishDate | 2022 |
| publisher | Lippincott, Williams & Wilkins |
| record_format | dspace |
| spelling | oxford-uuid:7dcfdf9d-3b6b-400d-b1d6-68dceeb68c6b2023-03-10T12:23:15ZMorbidity and associated factors of depressive disorder in patients with Parkinson's diseaseJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7dcfdf9d-3b6b-400d-b1d6-68dceeb68c6bEnglishSymplectic ElementsLippincott, Williams & Wilkins2022Lee, YChiou, Y-JChang, Y-YHung, C-FChen, Y-FLin, T-KWang, L-JParkinson's disease (PD) is a progressive, neurodegenerative disorder and is commonly comorbid with depression. The aim of this cross-sectional study was to assess morbidity and associated factors of depression in patients with PD. In total, 181 patients with PD were enrolled and assessed using the Mini-International Neuropsychiatric Interview. Of the sample, 51% had at least one psychiatric diagnosis. The most prevalent psychiatric disorder was depressive disorder (27.6%), followed by rapid eye movement sleep behavior disorder (9.9%), insomnia disorder (8.8%), and adjustment disorder (2.8%). Severity of anxiety, suicide risk, and anxiolytics/hypnotics use were factors associated with depressive disorder in PD patients. Furthermore, severity of anxiety was significantly linked with suicide risk. We suggest that use of a standardized structured interview for early detection of depression in PD patients is crucial. Anxiety, anxiolytics/hypnotics use, depression, and suicide risks are interrelated and warrant clinical concerns regarding PD patients. |
| spellingShingle | Lee, Y Chiou, Y-J Chang, Y-Y Hung, C-F Chen, Y-F Lin, T-K Wang, L-J Morbidity and associated factors of depressive disorder in patients with Parkinson's disease |
| title | Morbidity and associated factors of depressive disorder in patients with Parkinson's disease |
| title_full | Morbidity and associated factors of depressive disorder in patients with Parkinson's disease |
| title_fullStr | Morbidity and associated factors of depressive disorder in patients with Parkinson's disease |
| title_full_unstemmed | Morbidity and associated factors of depressive disorder in patients with Parkinson's disease |
| title_short | Morbidity and associated factors of depressive disorder in patients with Parkinson's disease |
| title_sort | morbidity and associated factors of depressive disorder in patients with parkinson s disease |
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