Parent-of-origin of HLA-DRB1*1501 and age of onset of multiple sclerosis.

Parent-of-origin of HLA-DRB1*1501 and age of onset of multiple sclerosis.

Multiple sclerosis (MS) is a complex neurological trait. Allelic variation in the MHC class II region exerts the single strongest effect on MS genetic risk. The clinical onset of the disease is extremely variable, and can range from the first to the ninth decade of life. Epidemiological studies have...

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Bibliographic Details
Main Authors: Ramagopalan, S, Byrnes, J, Dyment, D, Guimond, C, Handunnetthi, L, Disanto, G, Yee, I, Ebers, G, Sadovnick, A
Format: Journal article
Language:English
Published: 2009

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