CAMPATH-1H in inflammatory arthritis.
CAMPATH-1H is a humanised mAb directed against lymphocytes. This mAb has been used to treat patients with rheumatoid arthritis. Clinical improvement with reduction in the Ritchie index and joint score has lasted for up to 8 months in some patients. A profound and prolonged lymphopaenia is induced by...
| Main Authors: | , , , , |
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| Format: | Conference item |
| Published: |
1993
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| _version_ | 1797077934994882560 |
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| author | Watts, R Isaacs, J Hale, G Hazleman, B Waldmann, H |
| author_facet | Watts, R Isaacs, J Hale, G Hazleman, B Waldmann, H |
| author_sort | Watts, R |
| collection | OXFORD |
| description | CAMPATH-1H is a humanised mAb directed against lymphocytes. This mAb has been used to treat patients with rheumatoid arthritis. Clinical improvement with reduction in the Ritchie index and joint score has lasted for up to 8 months in some patients. A profound and prolonged lymphopaenia is induced by the mAb, with CD4+ numbers remaining suppressed for up to one year. |
| first_indexed | 2024-03-07T00:25:10Z |
| format | Conference item |
| id | oxford-uuid:7de70dc9-63dd-4b28-a640-5f87ee6d206c |
| institution | University of Oxford |
| last_indexed | 2024-03-07T00:25:10Z |
| publishDate | 1993 |
| record_format | dspace |
| spelling | oxford-uuid:7de70dc9-63dd-4b28-a640-5f87ee6d206c2022-03-26T21:06:44ZCAMPATH-1H in inflammatory arthritis.Conference itemhttp://purl.org/coar/resource_type/c_5794uuid:7de70dc9-63dd-4b28-a640-5f87ee6d206cSymplectic Elements at Oxford1993Watts, RIsaacs, JHale, GHazleman, BWaldmann, HCAMPATH-1H is a humanised mAb directed against lymphocytes. This mAb has been used to treat patients with rheumatoid arthritis. Clinical improvement with reduction in the Ritchie index and joint score has lasted for up to 8 months in some patients. A profound and prolonged lymphopaenia is induced by the mAb, with CD4+ numbers remaining suppressed for up to one year. |
| spellingShingle | Watts, R Isaacs, J Hale, G Hazleman, B Waldmann, H CAMPATH-1H in inflammatory arthritis. |
| title | CAMPATH-1H in inflammatory arthritis. |
| title_full | CAMPATH-1H in inflammatory arthritis. |
| title_fullStr | CAMPATH-1H in inflammatory arthritis. |
| title_full_unstemmed | CAMPATH-1H in inflammatory arthritis. |
| title_short | CAMPATH-1H in inflammatory arthritis. |
| title_sort | campath 1h in inflammatory arthritis |
| work_keys_str_mv | AT wattsr campath1hininflammatoryarthritis AT isaacsj campath1hininflammatoryarthritis AT haleg campath1hininflammatoryarthritis AT hazlemanb campath1hininflammatoryarthritis AT waldmannh campath1hininflammatoryarthritis |