Investigating brain dynamics and connectivity with functional MRI

Functional Magnetic Resonance Imaging (fMRI) scans provide a record of ongoing neural processing through the measurement of changes in regional levels of blood oxygenation. While subjects are resting, fMRI has revealed networks of brain regions exhibiting synchronised 0.02 - 0.12 Hz fluctuations in...

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Main Authors: Duff, E, Egan, G, Cunnington, R, Mareels, I, Wang, B, Fox, P, Xiong, J
Format: Conference item
Published: 2004
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author Duff, E
Egan, G
Cunnington, R
Mareels, I
Wang, B
Fox, P
Xiong, J
author_facet Duff, E
Egan, G
Cunnington, R
Mareels, I
Wang, B
Fox, P
Xiong, J
author_sort Duff, E
collection OXFORD
description Functional Magnetic Resonance Imaging (fMRI) scans provide a record of ongoing neural processing through the measurement of changes in regional levels of blood oxygenation. While subjects are resting, fMRI has revealed networks of brain regions exhibiting synchronised 0.02 - 0.12 Hz fluctuations in spontaneous, low frequency brain activity. The physiology underlying these 'resting state' fluctuations is poorly understood. Our current research investigates these networks within the human motor system, assessing their persistence over time, their covariance structure, and the effects that motor performance and training have on the networks. Here we present a review of this study, focusing on the methods involved in assessing the fMRI data, discussing issues of region identification, signal extraction, signal to noise, network covariance analysis and the detection of changes in the networks. © 2004 IEEE.
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spelling oxford-uuid:7df2076a-67e5-4250-b586-e8c1df6704172022-03-26T21:06:53ZInvestigating brain dynamics and connectivity with functional MRIConference itemhttp://purl.org/coar/resource_type/c_5794uuid:7df2076a-67e5-4250-b586-e8c1df670417Symplectic Elements at Oxford2004Duff, EEgan, GCunnington, RMareels, IWang, BFox, PXiong, JFunctional Magnetic Resonance Imaging (fMRI) scans provide a record of ongoing neural processing through the measurement of changes in regional levels of blood oxygenation. While subjects are resting, fMRI has revealed networks of brain regions exhibiting synchronised 0.02 - 0.12 Hz fluctuations in spontaneous, low frequency brain activity. The physiology underlying these 'resting state' fluctuations is poorly understood. Our current research investigates these networks within the human motor system, assessing their persistence over time, their covariance structure, and the effects that motor performance and training have on the networks. Here we present a review of this study, focusing on the methods involved in assessing the fMRI data, discussing issues of region identification, signal extraction, signal to noise, network covariance analysis and the detection of changes in the networks. © 2004 IEEE.
spellingShingle Duff, E
Egan, G
Cunnington, R
Mareels, I
Wang, B
Fox, P
Xiong, J
Investigating brain dynamics and connectivity with functional MRI
title Investigating brain dynamics and connectivity with functional MRI
title_full Investigating brain dynamics and connectivity with functional MRI
title_fullStr Investigating brain dynamics and connectivity with functional MRI
title_full_unstemmed Investigating brain dynamics and connectivity with functional MRI
title_short Investigating brain dynamics and connectivity with functional MRI
title_sort investigating brain dynamics and connectivity with functional mri
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