AN EFFECTIVE SUBSTITUTE FOR ALPHA-AMINOADIPIC ACID IN THE ENZYMATIC-SYNTHESIS OF PENICILLINS
meta-Carboxyphenylacetylcysteinylvaline has been demonstrated to be a highly efficient substrate for the enzyme isopenicillin N synthetase with similar Michaelis constants and maximum velocity parameters to the natural substrate δ-(L-α-aminoadipoyl)-L-cysteinyl-D-valine.
Bibliographic Details
| Main Authors: |
Baldwin, J,
Adlington, R,
Crabbe, M,
Knight, G,
Nomoto, T,
Schofield, C |
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| Format: | Journal article
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| Language: | English |
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| Published: |
1987
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