A short stereoselective total synthesis of the fusarium toxin equisetin.
A short stereoselective synthesis of the fusarium toxin equisetin, an N-methylserine-derived acyl tetramic acid and potent inhibitor of HIV-1 integrase enzyme, is described using as the key step a stereoselective lithium perchlorate mediated intramolecular Diels-Alder reaction of a fully conjugated...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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2000
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| _version_ | 1826281262027898880 |
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| author | Burke, LT Dixon, D Ley, S Rodríguez, F |
| author_facet | Burke, LT Dixon, D Ley, S Rodríguez, F |
| author_sort | Burke, LT |
| collection | OXFORD |
| description | A short stereoselective synthesis of the fusarium toxin equisetin, an N-methylserine-derived acyl tetramic acid and potent inhibitor of HIV-1 integrase enzyme, is described using as the key step a stereoselective lithium perchlorate mediated intramolecular Diels-Alder reaction of a fully conjugated E,E,E-triene with a trisubstituted gamma,delta-unsaturated beta-ketothioester. |
| first_indexed | 2024-03-07T00:26:10Z |
| format | Journal article |
| id | oxford-uuid:7e344d90-a38f-4fed-8081-0db4c9f3d297 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:26:10Z |
| publishDate | 2000 |
| record_format | dspace |
| spelling | oxford-uuid:7e344d90-a38f-4fed-8081-0db4c9f3d2972022-03-26T21:08:45ZA short stereoselective total synthesis of the fusarium toxin equisetin.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7e344d90-a38f-4fed-8081-0db4c9f3d297EnglishSymplectic Elements at Oxford2000Burke, LTDixon, DLey, SRodríguez, FA short stereoselective synthesis of the fusarium toxin equisetin, an N-methylserine-derived acyl tetramic acid and potent inhibitor of HIV-1 integrase enzyme, is described using as the key step a stereoselective lithium perchlorate mediated intramolecular Diels-Alder reaction of a fully conjugated E,E,E-triene with a trisubstituted gamma,delta-unsaturated beta-ketothioester. |
| spellingShingle | Burke, LT Dixon, D Ley, S Rodríguez, F A short stereoselective total synthesis of the fusarium toxin equisetin. |
| title | A short stereoselective total synthesis of the fusarium toxin equisetin. |
| title_full | A short stereoselective total synthesis of the fusarium toxin equisetin. |
| title_fullStr | A short stereoselective total synthesis of the fusarium toxin equisetin. |
| title_full_unstemmed | A short stereoselective total synthesis of the fusarium toxin equisetin. |
| title_short | A short stereoselective total synthesis of the fusarium toxin equisetin. |
| title_sort | short stereoselective total synthesis of the fusarium toxin equisetin |
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