A short stereoselective total synthesis of the fusarium toxin equisetin.

A short stereoselective synthesis of the fusarium toxin equisetin, an N-methylserine-derived acyl tetramic acid and potent inhibitor of HIV-1 integrase enzyme, is described using as the key step a stereoselective lithium perchlorate mediated intramolecular Diels-Alder reaction of a fully conjugated...

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Main Authors: Burke, LT, Dixon, D, Ley, S, Rodríguez, F
格式: Journal article
語言:English
出版: 2000