Production of low-avidity antibody by infants after infection with serogroup B meningococci.

Experimental serogroup B meningococcal vaccines have induced only poor immune responses and have had little protective efficacy in children younger than 1 year of age. We used ELISA with potassium thiocyanate to compare the average avidity of antibody produced by infants with that of children older...

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Autors principals: Pollard, A, Levin, M
Format: Journal article
Idioma:English
Publicat: 2000