Diagnostics for typhoid fever: current perspectives and future outlooks for product development and access

Typhoid is an enteric disease caused by <i>Salmonella</i> Typhi. Like many febrile illnesses, typhoid presents with nonspecific symptoms. In routine healthcare settings in low- and middle-income countries, typhoid fever is suspected and treated empirically. Though many diagnostic tests a...

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Chi tiết về thư mục
Những tác giả chính: Sapkota, J, Roberts, T, Basnyat, B, Baker, S, Hampton, LM, Dittrich, S
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Oxford University Press 2023
Miêu tả
Tóm tắt:Typhoid is an enteric disease caused by <i>Salmonella</i> Typhi. Like many febrile illnesses, typhoid presents with nonspecific symptoms. In routine healthcare settings in low- and middle-income countries, typhoid fever is suspected and treated empirically. Though many diagnostic tests are available for typhoid diagnosis, there are currently no diagnostic tests that meet ideal requirements for sensitivity, specificity, speed, and cost-effectiveness. With introduction of typhoid conjugate vaccine, it is essential to explore the current and future typhoid approach in the context of use case and access to ensure their utilization for disease control.