| Summary: | This article looks at the scientific studies and debates that surrounded the control of nagana (trypanosomosis in livestock) in Zululand, South Africa, from the late nineteenth century until the 1950s. By 1953 the disease appeared to be contained following the use of DDT to exterminate the tsetse fly that spread the infection from immune wildlife to susceptible livestock. It argues that South Africa made an important contribution to western knowledge about trypanosomosis in terms of ots etiology and possibilities for its control - a fact that has often been overlooked in the historical literature that has tended to focus on events in colonial central and east Africa. It explores Zulu conceptualizations of nagana, which influenced early researchers, the evolution of veterinary, entomological, and ecological sciences as "tools" for understanding and suppresing disease, as well as the difficulties involved in reconciling game conservation with colonial settlement. The article also shows how an animal disease contributed to the development of colonial science and encouraged the expansion of scientific networks with African colonies and beyond.
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