Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex.

beta-Lactam inhibitors of transpeptidase enzymes involved in cell wall biosynthesis remain among the most important therapeutic agents in clinical use. beta-Lactams have more recently been developed as inhibitors of serine proteases including elastase. All therapeutically useful beta-lactam inhibito...

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Hlavní autoři: Wilmouth, R, Westwood, N, Anderson, K, Brownlee, W, Claridge, T, Clifton, I, Pritchard, G, Aplin, RT, Schofield, C
Médium: Journal article
Jazyk:English
Vydáno: 1998

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