Developing inhibitors of bromodomain-histone interactions
<p>Lysine acetylation is a widespread protein post-translational modification that influences diverse cellular processes. An association between acetylation of histone N-terminal tails and transcriptional activation has been recognised since the 1960s. However, it has only become apparent sinc...
Autor Principal: | Hewings, D |
---|---|
Outros autores: | Conway, S |
Formato: | Thesis |
Idioma: | English |
Publicado: |
2014
|
Subjects: |
Títulos similares
-
Development of small molecule inhibitors of the bromodomain-histone interaction
por: Rooney, TPC
Publicado: (2014) -
Design and synthesis of small molecule chemical probes for bromodomain-containing proteins.
por: Hay, D
Publicado: (2014) -
Palladium mediated allylic fluorination
por: Hollingworth, C
Publicado: (2013) -
Aziridinations of tethered allenes
por: Feast, GC
Publicado: (2011) -
Exploring and exploiting selectivity in Rhodium-catalysed hydroacylation reactions
por: Poingdestre, SJ
Publicado: (2012)