Developing inhibitors of bromodomain-histone interactions
<p>Lysine acetylation is a widespread protein post-translational modification that influences diverse cellular processes. An association between acetylation of histone N-terminal tails and transcriptional activation has been recognised since the 1960s. However, it has only become apparent sinc...
מחבר ראשי: | Hewings, D |
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מחברים אחרים: | Conway, S |
פורמט: | Thesis |
שפה: | English |
יצא לאור: |
2014
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נושאים: |
פריטים דומים
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Development of small molecule inhibitors of the bromodomain-histone interaction
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יצא לאור: (2014) -
Design and synthesis of small molecule chemical probes for bromodomain-containing proteins.
מאת: Hay, D
יצא לאור: (2014) -
Palladium mediated allylic fluorination
מאת: Hollingworth, C
יצא לאור: (2013) -
Aziridinations of tethered allenes
מאת: Feast, GC
יצא לאור: (2011) -
Exploring and exploiting selectivity in Rhodium-catalysed hydroacylation reactions
מאת: Poingdestre, SJ
יצא לאור: (2012)