Developing inhibitors of bromodomain-histone interactions

<p>Lysine acetylation is a widespread protein post-translational modification that influences diverse cellular processes. An association between acetylation of histone N-terminal tails and transcriptional activation has been recognised since the 1960s. However, it has only become apparent sinc...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur: Hewings, D
Awduron Eraill: Conway, S
Fformat: Traethawd Ymchwil
Iaith:English
Cyhoeddwyd: 2014
Pynciau: