Developing inhibitors of bromodomain-histone interactions
<p>Lysine acetylation is a widespread protein post-translational modification that influences diverse cellular processes. An association between acetylation of histone N-terminal tails and transcriptional activation has been recognised since the 1960s. However, it has only become apparent sinc...
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Format: | Thèse |
Langue: | English |
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2014
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