Developing inhibitors of bromodomain-histone interactions

<p>Lysine acetylation is a widespread protein post-translational modification that influences diverse cellular processes. An association between acetylation of histone N-terminal tails and transcriptional activation has been recognised since the 1960s. However, it has only become apparent sinc...

Полное описание

Библиографические подробности
Главный автор: Hewings, D
Другие авторы: Conway, S
Формат: Диссертация
Язык:English
Опубликовано: 2014
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