Polymorphisms in the glucokinase-associated, dual-specificity phosphatase 12 (DUSP12) gene under chromosome 1q21 linkage peak are associated with type 2 diabetes

Polymorphisms in the glucokinase-associated, dual-specificity phosphatase 12 (DUSP12) gene under chromosome 1q21 linkage peak are associated with type 2 diabetes

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Linkage of type 2 diabetes to chromosome 1q21-q23 is well replicated across populations. In an initial 50-kb marker map (580 markers) across the linked region, one of the two strongest associations observed in Utah Caucasians was at marker rs1503814 (P < 0.00001 in pools, P < 0.004 in...

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Bibliographische Detailangaben
Hauptverfasser: Das, S, Chu, W, Hale, T, Wang, X, Craig, R, Wang, H, Shuldiner, A, Froguel, P, Deloukas, P, McCarthy, M, Zeggini, E, Hasstedt, S, Elbein, S
Format: Journal article
Sprache:English
Veröffentlicht: 2006

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