DOC-MEK: A double-blind randomized phase II trial of docetaxel with or without selumetinib (AZD6244; ARRY-142886) in wt BRAF advanced melanoma

Eitemau Tebyg

• DOC-MEK: a double-blind randomized phase II trial of docetaxel with or without selumetinib in wild-type BRAF advanced melanoma.
  gan: Gupta, A, et al.
  Cyhoeddwyd: (2014)
• MEK1/2 blockade by AZD6244 (ARRY-142886) inhibits tumor growth and progression in an orthotopic human lung adenocarcinoma model with enhanced efficacy when combined with cediranib
  gan: Takahashi, O, et al.
  Cyhoeddwyd: (2009)
• AZD6244 (ARRY-142886) vs temozolomide (TMZ) in patients (pts) with advanced melanoma: An open-label, randomized, multicenter, phase II study
  gan: Dummer, R, et al.
  Cyhoeddwyd: (2008)
• Author Correction: Targeting inhibition of extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) suppresses growth and angiogenesis of gastric cancer
  gan: Jin-Hang Gao, et al.
  Cyhoeddwyd: (2022-03-01)
• A phase I, open-label, randomized crossover study to assess the effect of dosing of the MEK 1/2 inhibitor Selumetinib (AZD6244; ARRY-142866) in the presence and absence of food in patients with advanced solid tumors
  gan: Leijen, S, et al.
  Cyhoeddwyd: (2011)