Reversible acylation of elastase by gamma-lactam analogues of beta-lactam inhibitors
The reaction of a monocyclic γ-lactam with the serine protease elastase occurs via reversible formation of a hydrolytically labile acyl-enzyme complex; in contrast analogous β-lactam inhibitors irreversibly react to form a relatively stable acyl-enzyme complex.
| প্রধান লেখক: | , , , |
|---|---|
| বিন্যাস: | Journal article |
| ভাষা: | English |
| প্রকাশিত: |
1997
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