The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics.
Despite many decades of study, mitotic chromosome structure and composition remain poorly characterized. Here, we have integrated quantitative proteomics with bioinformatic analysis to generate a series of independent classifiers that describe the approximately 4,000 proteins identified in isolated...
Автори: | Ohta, S, Bukowski-Wills, J, Sanchez-Pulido, L, Alves, F, Wood, L, Chen, Z, Platani, M, Fischer, L, Hudson, D, Ponting, C, Fukagawa, T, Earnshaw, W, Rappsilber, J |
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Формат: | Journal article |
Мова: | English |
Опубліковано: |
2010
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