Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary.

Numerous studies have tested the association between TP53 mutations in ovarian cancer and prognosis but these have been consistently confounded by limitations in study design, methodology, and/or heterogeneity in the sample cohort. High-grade serous (HGS) carcinoma is the most clinically important h...

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Hlavní autoři: Ahmed, A, Etemadmoghadam, D, Temple, J, Lynch, A, Riad, M, Sharma, R, Stewart, C, Fereday, S, Caldas, C, Defazio, A, Bowtell, D, Brenton, J
Médium: Journal article
Jazyk:English
Vydáno: 2010