Resting-state fMRI in the Human Connectome Project.
Resting-state functional magnetic resonance imaging (rfMRI) allows one to study functional connectivity in the brain by acquiring fMRI data while subjects lie inactive in the MRI scanner, and taking advantage of the fact that functionally related brain regions spontaneously co-activate. rfMRI is one...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2013
|
| _version_ | 1826281462845931520 |
|---|---|
| author | Smith, S Beckmann, C Andersson, J Auerbach, E Bijsterbosch, J Douaud, G Duff, E Feinberg, D Griffanti, L Harms, M Kelly, M Laumann, T Miller, K Moeller, S Petersen, S Power, J Salimi-Khorshidi, G Snyder, A Vu, A Woolrich, M Xu, J Yacoub, E Uğurbil, K Van Essen, D Glasser, M |
| author_facet | Smith, S Beckmann, C Andersson, J Auerbach, E Bijsterbosch, J Douaud, G Duff, E Feinberg, D Griffanti, L Harms, M Kelly, M Laumann, T Miller, K Moeller, S Petersen, S Power, J Salimi-Khorshidi, G Snyder, A Vu, A Woolrich, M Xu, J Yacoub, E Uğurbil, K Van Essen, D Glasser, M |
| author_sort | Smith, S |
| collection | OXFORD |
| description | Resting-state functional magnetic resonance imaging (rfMRI) allows one to study functional connectivity in the brain by acquiring fMRI data while subjects lie inactive in the MRI scanner, and taking advantage of the fact that functionally related brain regions spontaneously co-activate. rfMRI is one of the two primary data modalities being acquired for the Human Connectome Project (the other being diffusion MRI). A key objective is to generate a detailed in vivo mapping of functional connectivity in a large cohort of healthy adults (over 1000 subjects), and to make these datasets freely available for use by the neuroimaging community. In each subject we acquire a total of 1h of whole-brain rfMRI data at 3 T, with a spatial resolution of 2×2×2 mm and a temporal resolution of 0.7s, capitalizing on recent developments in slice-accelerated echo-planar imaging. We will also scan a subset of the cohort at higher field strength and resolution. In this paper we outline the work behind, and rationale for, decisions taken regarding the rfMRI data acquisition protocol and pre-processing pipelines, and present some initial results showing data quality and example functional connectivity analyses. |
| first_indexed | 2024-03-07T00:29:11Z |
| format | Journal article |
| id | oxford-uuid:7f2c5466-e8b7-4f2d-b337-975d5ff82c8b |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:29:11Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | oxford-uuid:7f2c5466-e8b7-4f2d-b337-975d5ff82c8b2022-03-26T21:15:09ZResting-state fMRI in the Human Connectome Project.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7f2c5466-e8b7-4f2d-b337-975d5ff82c8bEnglishSymplectic Elements at Oxford2013Smith, SBeckmann, CAndersson, JAuerbach, EBijsterbosch, JDouaud, GDuff, EFeinberg, DGriffanti, LHarms, MKelly, MLaumann, TMiller, KMoeller, SPetersen, SPower, JSalimi-Khorshidi, GSnyder, AVu, AWoolrich, MXu, JYacoub, EUğurbil, KVan Essen, DGlasser, MResting-state functional magnetic resonance imaging (rfMRI) allows one to study functional connectivity in the brain by acquiring fMRI data while subjects lie inactive in the MRI scanner, and taking advantage of the fact that functionally related brain regions spontaneously co-activate. rfMRI is one of the two primary data modalities being acquired for the Human Connectome Project (the other being diffusion MRI). A key objective is to generate a detailed in vivo mapping of functional connectivity in a large cohort of healthy adults (over 1000 subjects), and to make these datasets freely available for use by the neuroimaging community. In each subject we acquire a total of 1h of whole-brain rfMRI data at 3 T, with a spatial resolution of 2×2×2 mm and a temporal resolution of 0.7s, capitalizing on recent developments in slice-accelerated echo-planar imaging. We will also scan a subset of the cohort at higher field strength and resolution. In this paper we outline the work behind, and rationale for, decisions taken regarding the rfMRI data acquisition protocol and pre-processing pipelines, and present some initial results showing data quality and example functional connectivity analyses. |
| spellingShingle | Smith, S Beckmann, C Andersson, J Auerbach, E Bijsterbosch, J Douaud, G Duff, E Feinberg, D Griffanti, L Harms, M Kelly, M Laumann, T Miller, K Moeller, S Petersen, S Power, J Salimi-Khorshidi, G Snyder, A Vu, A Woolrich, M Xu, J Yacoub, E Uğurbil, K Van Essen, D Glasser, M Resting-state fMRI in the Human Connectome Project. |
| title | Resting-state fMRI in the Human Connectome Project. |
| title_full | Resting-state fMRI in the Human Connectome Project. |
| title_fullStr | Resting-state fMRI in the Human Connectome Project. |
| title_full_unstemmed | Resting-state fMRI in the Human Connectome Project. |
| title_short | Resting-state fMRI in the Human Connectome Project. |
| title_sort | resting state fmri in the human connectome project |
| work_keys_str_mv | AT smiths restingstatefmriinthehumanconnectomeproject AT beckmannc restingstatefmriinthehumanconnectomeproject AT anderssonj restingstatefmriinthehumanconnectomeproject AT auerbache restingstatefmriinthehumanconnectomeproject AT bijsterboschj restingstatefmriinthehumanconnectomeproject AT douaudg restingstatefmriinthehumanconnectomeproject AT duffe restingstatefmriinthehumanconnectomeproject AT feinbergd restingstatefmriinthehumanconnectomeproject AT griffantil restingstatefmriinthehumanconnectomeproject AT harmsm restingstatefmriinthehumanconnectomeproject AT kellym restingstatefmriinthehumanconnectomeproject AT laumannt restingstatefmriinthehumanconnectomeproject AT millerk restingstatefmriinthehumanconnectomeproject AT moellers restingstatefmriinthehumanconnectomeproject AT petersens restingstatefmriinthehumanconnectomeproject AT powerj restingstatefmriinthehumanconnectomeproject AT salimikhorshidig restingstatefmriinthehumanconnectomeproject AT snydera restingstatefmriinthehumanconnectomeproject AT vua restingstatefmriinthehumanconnectomeproject AT woolrichm restingstatefmriinthehumanconnectomeproject AT xuj restingstatefmriinthehumanconnectomeproject AT yacoube restingstatefmriinthehumanconnectomeproject AT ugurbilk restingstatefmriinthehumanconnectomeproject AT vanessend restingstatefmriinthehumanconnectomeproject AT glasserm restingstatefmriinthehumanconnectomeproject |