Hedging against antiviral resistance during the next influenza pandemic using small stockpiles of an alternative chemotherapy

The effectiveness of single-drug antiviral interventions to reduce morbidity and mortality during the next influenza pandemic will be substantially weakened if transmissible strains emerge which are resistant to the stockpiled antiviral drugs. We developed a mathematical model to test the hypothesis...

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Bibliographic Details
Main Authors: Wu, J, Leung, G, Lipsitch, M, Cooper, B, Riley, S
Format: Journal article
Published: Public Library of Science 2009