Isoenzyme specific PFK-2/FBPas-2 inhibition as an anti-cancer strategy

Isoenzyme specific PFK-2/FBPas-2 inhibition as an anti-cancer strategy

<p>High aerobic glycolytic capacity is correlated with poor prognosis and increased tumour aggressiveness. 6Phosphofructo-1-kinase catalyses the first irreversible step of glycolysis, and is activated by fructose-2,6-bisphosphate, a product of the kinase activity of four bifunctional isoenzyme...

書誌詳細
第一著者:	Williams, J
その他の著者:	Harris, A
フォーマット:	学位論文
言語:	English
出版事項:	2013
主題:	Organic synthesis Enzymes Tumours Synthetic organic chemistry Metabolism Oncology

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