SDH mutations in cancer
The SDHA, SDHB, SDHC, SDHD genes encode the four subunits of succinate dehydrogenase (SDH; mitochondrial complex II), a mitochondrial enzyme involved in two essential energy-producing metabolic processes of the cell, the Krebs cycle and the electron transport chain. Germline loss-of-function mutatio...
Үндсэн зохиолчид: | Bardella, C, Pollard, P, Tomlinson, I |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
2011
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Ижил төстэй зүйлс
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SDH mutations in cancer.
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Expression of HIF-1a, HIF-2a (EPAS1), and their target genes in paraganglioma and phaeochromocytoma with VHL and SDH mutations
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