SDH mutations in cancer

The SDHA, SDHB, SDHC, SDHD genes encode the four subunits of succinate dehydrogenase (SDH; mitochondrial complex II), a mitochondrial enzyme involved in two essential energy-producing metabolic processes of the cell, the Krebs cycle and the electron transport chain. Germline loss-of-function mutatio...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Bardella, C, Pollard, P, Tomlinson, I
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2011