SDH mutations in cancer

The SDHA, SDHB, SDHC, SDHD genes encode the four subunits of succinate dehydrogenase (SDH; mitochondrial complex II), a mitochondrial enzyme involved in two essential energy-producing metabolic processes of the cell, the Krebs cycle and the electron transport chain. Germline loss-of-function mutatio...

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Detalhes bibliográficos
Main Authors: Bardella, C, Pollard, P, Tomlinson, I
Formato: Journal article
Idioma:English
Publicado em: 2011